Reading Time: 4 minutes The Pre-brief: A 33-year-old female presents to the emergency department (ED) in cardiac arrest from an outpatient cosmetic procedure. EMS…
overdose
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Reading Time: 4 minutes The Pre-brief EMS is bringing in a 42-year-old male found down on the sidewalk with a bag of heroin in…
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Reading Time: 3 minutes Overdose associated with synthetic opioids like fentanyl is a significant problem and is associated with an alarmingly high incidence of mortality and morbidity. A new preparation of high dose intranasal (IN) naloxone was just approved by the FDA to help combat this crisis. The currently available evidence to support its use, is marginal at best.
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Reading Time: 2 minutes Valproic acid is a broad-spectrum antiepileptic medication used to treat bipolar disorder, focal (partial) onset, and generalized onset seizures. While standard therapy in overdose involves the use of activated charcoal and levocarnitine, the interaction between carbapenem antibiotics and valproic acid has been effective in quickly reducing serum VPA levels.
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Reading Time: 3 minutes The Pre-brief Over 2 million Americans struggle with opioid use disorder In 2018, more than 67,000 lives were lost to…