Pharm & Tox

Reading Time: 4 minutes Outside of SCUBA diving injuries, carbon monoxide (CO) poisoning is the only other indication where hyperbaric oxygen therapy (HBOT) is considered primary therapy. In addition to expediting CO elimination, HBOT can, more importantly, reduce a patient’s chances of developing delayed neurologic sequelae (DNS) following CO poisoning.

Reading Time: 5 minutes Jordan had Pippen, Batman has Robin, peanut butter has jelly, and N-acetylcysteine (NAC) has… fomepizole? Fomepizole – yes, that fomepizole – is traditionally used for toxic alcohol poisoning, and recent evidence shows that it may also be useful when used in conjunction with NAC for massive acetaminophen overdose.

Reading Time: 2 minutes The Pre-brief Today we’ll be discussing the management of 3 gastrointestinal hiccups (pun intended) commonly dealt with in the ICU:…

Reading Time: 4 minutes The Pre-brief DKA patients are common in our ED. Diagnosis and treatment are standard with the utilization of a continuous…

Reading Time: 2 minutes The Pre-brief Extracorporeal membrane oxygenation (ECMO) provides mechanical support for the treatment of cardiac or respiratory failure. Highly protein bound…

Reading Time: 4 minutes From competitive inhibitors to monoclonal antibodies: what are your options for reversing the direct oral anticoagulants in intracranial hemorrhage?

Reading Time: 4 minutes Many practitioners have very little exposure and most patients have never heard of hyperbaric oxygen therapy (HBOT) until a patient needs it.

Reading Time: 4 minutes Complications of massive transfusion include electrolyte derangements, with hypocalcemia being one of the main clinically significant electrolyte abnormalities. Learrn why you should know about hypocalcemia in trauma

Reading Time: 2 minutes Urine drug screens (UDS) can be useful tools for critical care providers to determine if a patient is acutely intoxicated or has overdosed on a substance. However, there are pitfalls to using UDS.

Reading Time: 2 minutes Valproic acid is a broad-spectrum antiepileptic medication used to treat bipolar disorder, focal (partial) onset, and generalized onset seizures. While standard therapy in overdose involves the use of activated charcoal and levocarnitine, the interaction between carbapenem antibiotics and valproic acid has been effective in quickly reducing serum VPA levels.